In an orthotopic mice model of Neuroblastoma (NB) transplant, DMFAT loaded with PTX prevents or delays NB relapse when placed in the surgical area of tumor resection, without any collateral toxicity. We concluded that MFAT, but also DMFAT, may represent very innovative natural biomaterials able to localize and release anti-cancer molecules at the tumor site, helping to fight cancer in human.
Microfragmented human fat tissue is a natural scaffold for drug delivery: Potential application in cancer chemotherapy
May 28, 2019
Journal of Controlled Release Volume 302