{"id":1680,"date":"2024-05-05T18:14:40","date_gmt":"2024-05-06T01:14:40","guid":{"rendered":"https:\/\/jointechlabs.com\/?post_type=industry-research&p=1680"},"modified":"2024-05-06T15:13:24","modified_gmt":"2024-05-06T22:13:24","slug":"clinical-evaluation-of-safety-and-efficacy-of-a-central-current-good-manufacturing-practices-laboratory-produced-autologous-adipose-derived-stromal-vascular-fraction-cell-therapy-product-for-the-treat","status":"publish","type":"industry-research","link":"https:\/\/jointechlabs.com\/it\/industry-research\/clinical-evaluation-of-safety-and-efficacy-of-a-central-current-good-manufacturing-practices-laboratory-produced-autologous-adipose-derived-stromal-vascular-fraction-cell-therapy-product-for-the-treat\/","title":{"rendered":"Valutazione clinica della sicurezza e dell'efficacia di un prodotto per la terapia con frazioni cellulari vascolari autologhe di derivazione adiposa prodotte dal laboratorio centrale di buone pratiche di fabbricazione per il trattamento dell'osteoartrite del ginocchio - Jointechlabs, Inc."},"content":{"rendered":"

Uno studio clinico a braccio singolo, in aperto, multisito, approvato dalla FDA, su pazienti con Kellgren-Lawrence di grado di gravit\u00e0 2-4 KOA. Il prodotto cellulare \u00e8 stato fabbricato a partire da un lipoaspirato specifico del paziente in uno stabilimento di produzione centrale conforme alla FDA. Ventinove soggetti sono stati trattati con una singola iniezione intra-articolare di SVF prodotto in GMP e sottoposto a test di qualit\u00e0. Durante il periodo di studio sono stati monitorati gli eventi avversi, i valori di laboratorio, i segni vitali e i risultati dell'esame fisico. \u00c8 stata dimostrata una solida tollerabilit\u00e0, senza sostanziali problemi di sicurezza. Il dolore e la funzionalit\u00e0 del ginocchio, valutati attraverso il Knee Injury and Osteoarthritis Outcome Score (KOOS), hanno mostrato notevoli miglioramenti. Questi benefici positivi si sono mantenuti fino a 12 mesi e la maggior parte dei partecipanti si \u00e8 dichiarata soddisfatta.<\/p>","protected":false},"featured_media":0,"template":"","class_list":["post-1680","industry-research","type-industry-research","status-publish","hentry"],"acf":[],"yoast_head":"\nClinical Evaluation of Safety and Efficacy of a Central Current Good Manufacturing Practices Laboratory Produced Autologous Adipose-Derived Stromal Vascular Fraction Cell Therapy Product for the Treatment of Knee Osteoarthritis - Jointechlabs, Inc<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/jointechlabs.com\/it\/industry-research\/clinical-evaluation-of-safety-and-efficacy-of-a-central-current-good-manufacturing-practices-laboratory-produced-autologous-adipose-derived-stromal-vascular-fraction-cell-therapy-product-for-the-treat\/\" \/>\n<meta property=\"og:locale\" content=\"it_IT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Clinical Evaluation of Safety and Efficacy of a Central Current Good Manufacturing Practices Laboratory Produced Autologous Adipose-Derived Stromal Vascular Fraction Cell Therapy Product for the Treatment of Knee Osteoarthritis\" \/>\n<meta property=\"og:description\" content=\"A single-arm, open-label, multisite, FDA approved clinical study in Kellgren-Lawrence severity grade 2-4 KOA patients. 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